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Summary
Julian Bauer is a PhD student, located in the group of Optical Technologies at the Institute of Medical Biotechnology of the Friedrich-Alexander University Erlangen-Nürnberg, in Erlangen, Germany. His PhD research focuses on developing a miniaturized modular bioreactor environment that allows for standardized parallel observation, analysis, and cultivation of biological samples in varying test conditions and environments, utilizing cutting-edge imaging technology like multiphoton or selective plane illumination microscopy. This strong emphasis on combining bioreactor engineering with advanced imaging technology was also reflected in his previous research activities as a student worker and especially during the course of his bachelor’s and master’s theses in Life Science Engineering. In both instances, Julian’s major focus lay on the investigation of the impact of elevated hydrostatic pressure levels on skeletal muscle tissue or single skeletal muscle cells. Hereby, he utilized a self-developed high-pressure microscopy chamber in conjunction with multiphoton fluorescence and label-free second-harmonic generation microscopy. However, this expertise in artificially mimicking deep-sea conditions with the ability to simultaneously gather morphological information of the pressurized tissue can also be applied to a broad variety of sample types, such as cartilage. Therefore, Julian’s contribution to the Cartilage Research Theme in the MPQC is the investigation of the effect of high hydrostatic pressures on shark cartilage with the aim to correlate pressure-induced morphological or structural changes within the tissue with the viscoelastic mechanical characteristics of this type of tissue.
Research Focus
High-pressure Biotechnology, Multiphoton Imaging, Bioreactor Engineering, Biophotonics, Image Analysis