Our Research

Our world-renowned researchers and use novel culture-independent molecular approaches and bioinformatics tools to answer important questions about the role of microbial communities in human and environmental health.

Research Programs


Recent Publications

PoroFluidics: deterministic fluid control in porous microfluidics

Wang, Zhongzheng, Ong, Louis Jun Ye, Gan, Yixiang, Pereira, Jean Michel, Zhang, Jun, Kasetsirikul, Surasak, Toh, Yi Chin, Sauret, Emilie (2024) PoroFluidics: deterministic fluid control in porous microfluidics. Lab on a Chip, 24 (17), pp.4050-4059.
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Cyclic tachyplesin I kills proliferative, non-proliferative and drug-resistant melanoma cells without inducing resistance

Benfield, Aurelie, Vernen, Felicitas, Young, Reuben, Nadal Bufi, Ferran, Lamb, Henry, Hammerlindl, Heinz, Craik, David J., Schaider, Helmut, Lawrence, Nicole, Blanksby, Stephen, et al. (2024) Cyclic tachyplesin I kills proliferative, non-proliferative and drug-resistant melanoma cells without inducing resistance. Pharmacological Research, 207, pp.Article number: 107298.
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Phylogenetic reconciliation: making the most of genomes to understand microbial ecology and evolution

Williams, Tom A., Davin, Adrian A., Szantho, Lenard l., Stamatakis, Alexandros, Wahl, Noah A., Woodcroft, Ben J., Soo, Rochelle M., Eme, Laura, Sheridan, Paul O., Gubry-Rangin, Cecile, et al. (2024) Phylogenetic reconciliation: making the most of genomes to understand microbial ecology and evolution. The ISME Journal, 18 (1), pp.Article number: wrae129.
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Discovery of antimicrobial peptides in the global microbiome with machine learning

Santos-Junior, Celio Dias, Torres, Marcelo D.T., Duan, Yiqian, Rodriguez del Rio, Alvaro, Schmidt, Thomas S.B., Chong, Hui, Fullam, Anthony, Kuhn, Michael, Zhu, Chengkai, Houseman, Amy, et al. (2024) Discovery of antimicrobial peptides in the global microbiome with machine learning. Cell, 187 (14), pp.3761-3778.e16.
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Localized Oxygen Control in a Microfluidic Osteochondral Interface Model Recapitulates Bone-Cartilage Crosstalk During Osteoarthritis

Ong, Louis Jun Ye, Sun, Antonia Rujia, Wang, Zhongzheng, Lee, Jayden, Prasadam, Indira, Toh, Yi Chin (2024) Localized Oxygen Control in a Microfluidic Osteochondral Interface Model Recapitulates Bone-Cartilage Crosstalk During Osteoarthritis. Advanced Functional Materials, 34 (28), pp.Article number: 2315608.
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Crawling, climbing, perching, and flying by FiBa soft robots

Ching, Terry, Lee, Joseph Zhi Wei, Win, Shane Kyi Hla, Win, Luke Soe Thura, Sufiyan, Danial, Lim, Charlotte Pei Xuan, Nagaraju, Nidhi, Toh, Yi Chin, Foong, Shaohui, Hashimoto, Michinao (2024) Crawling, climbing, perching, and flying by FiBa soft robots. Science Robotics, 9 (92), pp.Article number: eadk4533.
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Anaerobic methanotroph ‘Candidatus Methanoperedens nitroreducens’ has a pleomorphic life cycle

McIlroy, Simon J., Leu, Andy O., Zhang, Xueqin, Newell, Rhys, Woodcroft, Ben J., Yuan, Zhiguo, Hu, Shihu, Tyson, Gene W. (2023) Anaerobic methanotroph ‘Candidatus Methanoperedens nitroreducens’ has a pleomorphic life cycle. Nature Microbiology, 8 (2), pp.321-331.
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Phylogenetic and metabolic diversity of microbial communitiesperforming anaerobic ammonium and methane oxidations under different nitrogen loadings

Li, Jie, Liu, Tao, McIlroy, Simon, Tyson, Gene, Guo, Jianhua (2023) Phylogenetic and metabolic diversity of microbial communities performing anaerobic ammonium and methane oxidations under different nitrogen loadings. ISME Communications, 3, pp.Article number: 39.

Isolation and characterisation of novel Methanocorpusculum species indicates the genus is ancestrally host-associated

James G. Volmer, Rochelle M. Soo, Paul N. Evans, Emily C. Hoedt, Ana L. Astorga Alsina, Benjamin J. Woodcroft, Gene W. Tyson, Philip Hugenholtz & Mark Morrison (2023) Isolation and characterisation of novel Methanocorpusculum species indicates the genus is ancestrally host-associated. BMC Biology.

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Anaerobic oxidation of propane coupled to nitrate reduction by a lineage within the class Symbiobacteriia

Wu, Mengxiong, Li, Jie, Leu, Andy, Erler, Dirk, Stark, Terra, Tyson, Gene, Yuan, Zhiguo, McIlroy, Simon, Guo, Jianhua (2022) Anaerobic oxidation of propane coupled to nitrate reduction by a lineage within the class Symbiobacteriia. Nature Communications, 13 (1), pp.Article number: 6115.
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Other Publications

A full list of CMR research publications can be found on the CMR Google Scholar listing.