Our Research

Our world-renowned researchers and use novel culture-independent molecular approaches and bioinformatics tools to answer important questions about the role of microbial communities in human and environmental health.

Research Programs


Recent Publications

A global survey of prokaryotic genomes reveals the eco-evolutionary pressures driving horizontal gene transfer

Dmitrijeva, Marija, Tackmann, Janko, Matias Rodrigues, Joao Frederico, Huerta-Cepas, Jaime, Coelho, Luis Pedro, von Mering, Christian (2024) A global survey of prokaryotic genomes reveals the eco-evolutionary pressures driving horizontal gene transfer. Nature Ecology and Evolution, 8 (5), pp.986-998.
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Microbial polyphenol metabolism is part of the thawing permafrost carbon cycle

McGivern, Bridget B., Cronin, Dylan R., Ellenbogen, Jared B, Borton, Mikayla A, Knutson, Eleanor L, Freire-Zapata, Viviana, Bouranis, John A, Bernhardt, Lukas, Hernandez, Alma I, Flynn, Rory M, et al. (2024) Microbial polyphenol metabolism is part of the thawing permafrost carbon cycle. Nature Microbiology, 9 (6), pp.1454-1466.
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Challenges in computational discovery of bioactive peptides in 'omics data

Coelho, Luis Pedro, Santos-Junior, Celio Dias, de la Fuente-Nunez, Cesar (2024) Challenges in computational discovery of bioactive peptides in 'omics data. Proteomics, 24 (12-13), pp.Article number: 2300105.
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Transcriptomic and proteomic changes associated with cobalamin-dependent propionate production by the rumen bacterium Xylanibacter ruminicola

Mahoney-Kurpe, Sam C., Palevich, Nikola, Gagic, Dragana, Biggs, Patrick J., Reid, Peter M., Altshuler, Ianina, Pope, Phil, Attwood, Graeme T., Moon, Christina D. (2024) Transcriptomic and proteomic changes associated with cobalamin-dependent propionate production by the rumen bacterium Xylanibacter ruminicola. mSystems, 9 (11), pp.e0086424.
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SPIRE: a Searchable, Planetary-scale mIcrobiome REsource

Schmidt, Thomas S., Fullam, Anthony, Ferretti, Pamela, Orakov, Askarbek, Maistrenko, Oleksandr, Ruscheweyh, Hans, Letunic, Ivica, Duan, Yiqian, Rossum, Thea Van, Sunagawa, Shinichi, et al. (2024) SPIRE: a Searchable, Planetary-scale mIcrobiome REsource. Nucleic Acids Research, 52 (D1), pp.D777-D783.
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Osmoregulation in freshwater anaerobic methane-oxidizing archaea under salt stress

Echeveste Medrano, Maider J., Leu, Andy O., Pabst, Martin, Lin, Yuemei, McIlroy, Simon J., Tyson, Gene W., van Ede, Jitske, Sanchez-Andrea, Irene, Jetten, Mike S.M., Jansen, Robert, et al. (2024) Osmoregulation in freshwater anaerobic methane-oxidizing archaea under salt stress. The ISME Journal, 18 (1), pp.Article number: wrae137.
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Quantifying microbial DNA in metagenomes improves microbial trait estimation

Eisenhofer, Raphael, Alberdi, Antton, Woodcroft, Ben J. (2024) Quantifying microbial DNA in metagenomes improves microbial trait estimation. ISME Communications, 4 (1), pp.Article number: ycae111.
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3D-printed biomimetic scaffolds with precisely controlled and tunable structures guide cell migration and promote regeneration of osteochondral defect

Gu, Yuqing, Zou, Yiwei, Huang, Yuxuan, Liang, Renjie, Wu, Yicong, Hu, Yifan, Hong, Yi, Zhang, Xianzhu, Toh, Yi Chin, Ouyang, Hongwei, et al. (2024) 3D-printed biomimetic scaffolds with precisely controlled and tunable structures guide cell migration and promote regeneration of osteochondral defect. Biofabrication, 16 (1), pp.Article number: 015003.
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Methylotrophy in the Mire: direct and indirect routes for methane production in thawing permafrost

Ellenbogen, Jared B, Borton, Mikayla A., McGivern, Bridget B, Cronin, Dylan R., Hoyt, David W, Freire-Zapata, Viviana, McCalley, Carmody K., Varner, Ruth K., Crill, Patrick M., Wehr, Richard A., et al. (2024) Methylotrophy in the Mire: direct and indirect routes for methane production in thawing permafrost. mSystems, 9 (1), pp.Article number: e0069823.
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Machine learning and metagenomics identifies uncharacterized taxa inferred to drive biogeochemical cycles in a subtropical hypereutrophic estuary

Prabhu, Apoorva, Tule, Sanjana, Chuvochina, Maria, Boden, Mikael, McIlroy, Simon, Zaugg, Julian, Rinke, Christian (2024) Machine learning and metagenomics identifies uncharacterized taxa inferred to drive biogeochemical cycles in a subtropical hypereutrophic estuary. ISME Communications, 4 (1), pp.Article number: ycae067.
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Other Publications

A full list of CMR research publications can be found on the CMR Google Scholar listing.