Our Research

Our world-renowned researchers and use novel culture-independent molecular approaches and bioinformatics tools to answer important questions about the role of microbial communities in human and environmental health.

Research Programs


Recent Publications

3D-Printed Unibody Microfluidic Devices for Organ-on-Chip Applications

Ong, Louis Jun Ye, Kasetsirikul, Surasak, Milton, Laura A., Nie, Xiaolei, Eiken, Andrea W., Chirnside, James, Young, Lucy May Gillian, Nordin, Gregory P., Toh, Yi Chin (2025) 3D-Printed Unibody Microfluidic Devices for Organ-on-Chip Applications. Advanced Materials Technologies, 10 (22), pp.Article number: e01056.
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Structure and assembly of the MmpL5/MmpS5 efflux transporter from Mycobacterium tuberculosis

Xiong, Zhiqi, Yang, Xiaolin, Wang, Shule, Smart, Caitlan J., Sisson, Hazel M., Lin, Zhenli, Hu, Tianyu, Ran, Yuting, Xu, Chuyao, Yang, Xiuna, et al. (2025) Structure and assembly of the MmpL5/MmpS5 efflux transporter from Mycobacterium tuberculosis. Nature Communications, 16, pp.Article number: 4976.
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A framework for integrating genomics, microbial traits, and ecosystem biogeochemistry

Li, Zhen, Riley, William J., Marschmann, Gianna L., Karaoz, Ulas, Shirley, Ian A., Wu, Qiong, Bouskill, Nicholas J., Chang, Kuang Yu, Crill, Patrick M., Grant, Robert F., et al. (2025) A framework for integrating genomics, microbial traits, and ecosystem biogeochemistry. Nature Communications, 16 (1), pp.Article number: 2186.
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Potential for aerobic hydrocarbon oxidation in archaea

Leu, Andy O., Woodcroft, Ben J., McIlroy, Simon J., Tyson, Gene W. (2025) Potential for aerobic hydrocarbon oxidation in archaea. Nature Communications, 16 (1), pp.Article number: 9188.
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Metagenomics: a new frontier for routine pathology testing of gastrointestinal pathogens

Angel, Nicola Z., Sullivan, Mitchell J., Alsheikh-Hussain, Areej, Fang, Liang, MacDonald, Samantha, Pribyl, Alena, Wills, Blake, Tyson, Gene W., Hugenholtz, Philip, Parks, Donovan H., et al. (2025) Metagenomics: a new frontier for routine pathology testing of gastrointestinal pathogens. Gut Pathogens, 17, pp.Article number: 4.
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STREAMS guidelines: standards for technical reporting in environmental and host-associated microbiome studies

Kelliher, Julia M., Mirzayi, Chloe, Bordenstein, Sarah R., Oliver, Aaron, Kellogg, Christina A., Hatcher, Eneida L., Berg, Maureen, Baldrian, Petr, Aljumaah, Mashael, Miller, Cassandra Maria Luz, et al. (2025) STREAMS guidelines: standards for technical reporting in environmental and host-associated microbiome studies. Nature Microbiology, 10 (12), pp.3059-3068.
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Metagenomic analysis of fecal microbiomes reveals genetic potential for diverse hydrogen management strategies in marsupials

Bowerman, Kate L., Lu, Kenn, McRae, Harley, Volmer, James, Zaugg, Julian, Pope, Phil, HugenHoltz, Philip, Greening, Christopher, Morrison, Mark, Soo, Rochelle M., et al. (2025) Metagenomic analysis of fecal microbiomes reveals genetic potential for diverse hydrogen management strategies in marsupials. mSystems, pp.Article number: e01608-25.

Insights Into Phylogeny, Diversity and Functional Potential of Poseidoniales Viruses

Prabhu, Apoorva, Zaugg, Julian, Chan, Cheong Xin, McIlroy, Simon J., Rinke, Chris (2025) Insights Into Phylogeny, Diversity and Functional Potential of Poseidoniales Viruses. Environmental Microbiology, 27 (1), pp.Article number: e70017.
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GenomeFISH: genome-based fluorescence in situ hybridization for strain-level visualization of microbial communities

Engelberts, J. Pamela, Ye, Jun, Parks, Donovan H., McMaster, Eilish S., McInnes, Allison S., Woodcroft, Ben J., Volmer, James G., McIlroy, Simon J., Tyson, Gene W (2025) GenomeFISH: genome-based fluorescence in situ hybridization for strain-level visualization of microbial communities. The ISME Journal, 19 (1), pp.Article number: wraf138.
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Protozoal populations drive system-wide variation in the rumen microbiome

Kobel, Carl M., Leu, Andy, Vera Ponce de León, Arturo, Oyas, Ove, Lai, Wanxin, Altshuler, Ianina, Hagen, Live Heldal, Wollenberg, Rasmus Dam, Sondergaard, Mads T., Bakshani, Cassie R., et al. (2025) Protozoal populations drive system-wide variation in the rumen microbiome. Nature Communications, 16 (1), pp.Article number: 6238.
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Other Publications

A full list of CMR research publications can be found on the CMR Google Scholar listing.