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Project description
Drug-resistant infections are currently implicated in over 700,000 deaths per year worldwide. If we fail to find solutions to the rise of antibiotic resistance it is estimated that by 2050 this number will reach 10 million deaths per year. The threat lies not only in infections by multi-drug resistant bacteria but also in infections involving communities of bacteria that aggregate and form biofilms. These biofilms are resistant to antibiotics and cause infectious diseases that are hard to treat. However, there are very few strategies that exist to eradicate biofilms or have been approved for use in a clinical setting. This project aims to develop novel anti-biofilm agents.
Short Biography
Audrey received her BSc in Biochemistry from the University of Essex, England. She then completed her MSc in Drug Design and Discovery at the University of Salford (England), where she worked on the synthesis of small molecule heparin sulfate mimics as anti-cancer drugs under the supervision of Dr James Wilkinson. Audrey is interested in organic and medicinal chemistry.