Nitroxide-containing scaffolds for controlling biofilm-related infections

  • Nitroxide-containing scaffolds for controlling biofilm-related infections

Project dates: 2015-06-30 00:00:00 - 2021-06-30 00:00:00

Bacterial biofilms are a major problem in healthcare systems around the world as they cause persistent and chronic infections, including those associated with medical implants and cystic fibrosis. This project will develop new chemical approaches to deliver nitroxides at surface interfaces and in microparticles to facilitate long term control over biofilm growth. These functionalised scaffolds represent a breakthrough in the field and will have a profound impact by reducing infection rates associated with medical devices and improving airway clearance in cystic fibrosis patients.

Bacterial biofilms are a major problem in healthcare systems around the world as they cause persistent and chronic infections, including those associated with medical implants and cystic fibrosis. This project will develop new chemical approaches to deliver nitroxides at surface interfaces and in microparticles to facilitate long term control over biofilm growth. These functionalised scaffolds represent a breakthrough in the field and will have a profound impact by reducing infection rates associated with medical devices and improving airway clearance in cystic fibrosis patients.


Funding / Grants

  • Australian Research Council

Team

  • Prof Kathryn Fairfull-Smith - QUT Principal Investigator
  • Prof Yvonne Barner - Chief Investigator
  • Prof Robert Ernest W. Hancock - Partner Investigator