Associate Professor Nathalie Bock and Dr Jacqui McGovern
are transforming how we study cancers that affect the skeleton. The researchers are developing 3D tissue models that replicate the bone microenvironment, enabling them to investigate how tumour cells interact with surrounding bone and soft tissue. These models provide a more accurate platform for pre-clinical testing of new oncology drugs, reducing the high failure rates seen for these drug candidates in clinical trials. The shift from animal testing to advanced in vitro systems is also more ethical and stays ahead of upcoming regulatory changes. Beyond drug screening, Professor Bock has revealed that a common prostate cancer treatment can inadvertently promote tumour growth in bone, informing safer treatment strategies for metastasised prostate cancer. Dr McGovern is exploring targeted delivery systems to concentrate chemotherapy in bone tissue, minimising side effects.
Watch Jacqui talk about her research
Find A/Prof Bock’s QUT Academic Profile here.
Find Dr McGovern’s QUT Academic Profile here.
Read and download the Musculoskeletal Conditions Capability Statement
