Publications

Li, Zhixiu, Akar, Servet, Yarkan, Handan, Lee, Candice, Cetin, Pinar, Can, Gerçek, Kenar, Gokce, Capa, Fernur, Pamuk, Omer Nuri, Pehlivan, Yavuz, et al. (2019) Genome-wide association study in Turkish and Iranian populations identify rare familial Mediterranean fever gene (MEFV) polymorphisms associated with ankylosing spondylitis. PLoS Genetics, 15 (4), pp.Article number: e1008038 1-18.

Asquith, Mark, Sternes, Peter, Costello, Mary-Ellen, Karstens, Lisa, Diamond, Sarah, Martin, Tammy, Li, Zhixiu, Clout, Mhairi, Spector, Timothy, Le Cao, Kim-Anh, et al. (2019) HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome. Arthritis and Rheumatology, 71 (10), pp.1642-1650.

Reveille, John, Zhou, Xiaodong, Lee, MinJae, Weisman, Michael, Yi, Lin, Gensler, Lianne, Zou, Hejian, Ward, Michael, Ishimori, Mariko, Learch, Thomas, et al. (2019) HLA class I and II alleles in susceptibility to ankylosing spondylitis. Annals of the Rheumatic Diseases, 78 (1), pp.66-73.

Hanson, Aimee, Cuddihy, Thomas, Haynes, Katelin, Loo, Dorothy, Morton, Craig, Oppermann, Udo, Leo, Paul, Thomas, Gethin, Le Cao, Kim-Anh, Kenna, Tony, et al. (2018) Genetic variants in ERAP1 and ERAP2 associated with immune-mediated diseases influence protein expression and the isoform profile. Arthritis and Rheumatology, 70 (2), pp.255-265.

McInerney-Leo, Aideen, Wheeler, Lawrie, Sturm, Richard, Tan, Jean-Marie, Harris, Jessica, Anderson, Lisa, Jagirdar, Kasturee, Brown, Matt, Leo, Paul, Soyer, H. Peter, et al. (2018) Point mutation in p14ARF -specific exon 1β of CDKN2A causing familial melanoma and astrocytoma. British Journal of Dermatology, 178 (4), pp.e263-e264.

Gregson, Celia, Newell, Felicity, Leo, Paul, Clark, Graeme, Paternoster, Lavinia, Clout, Mhairi, Forgetta, Vincenzo, Morris, John, Ge, Bing, Bao, Xiao, et al. (2018) Genome-wide association study of extreme high bone mass: Contribution of common genetic variation to extreme BMD phenotypes and potential novel BMD-associated genes. Bone, 114, pp.62-71.

Bao, Xiao, Hanson, Aimee, Madeleine, Margaret, Wang, Sophia, Schwartz, Stephen, Newell, Felicity, Pettersson-Kymmer, Ulrika, Hemminki, Kari, Tiews, Sven, Steinberg, Winfried, et al. (2018) HLA and KIR associations of cervical neoplasia. Journal of Infectious Diseases, 218 (12), pp.2003-2015.

Cortes, Adrian, Gladman, Dafna, Raychaudhuri, Soumya, Cui, Jing, Wheeler, Lawrie, Brown, Matt (2018) Imputation-based analysis of MICA alleles in the susceptibility to ankylosing spondylitis. Annals of the Rheumatic Diseases, 77 (11), pp.1691-1692.

Blum, Stefan, Ji, Ying, Pennisi, David, Li, Zhixiu, Leo, Paul, McCombe, Pamela, Brown, Matt (2018) Genome-wide association study in Guillain-Barré syndrome. Journal of Neuroimmunology, 323, pp.109-114.

Leo, Paul, Madeleine, Margaret, Wang, Sophia, Schwartz, Stephen, Newell, Felicity, Brown, Matt, other, and (2017) Defining the genetic susceptibility to cervical neoplasia: A genome-wide association study. PLoS Genetics, 13 (8), pp.Article number: e1006866 1-20.

Li, Zhixiu, Haynes, Katelin, Pennisi, David, Anderson, Lisa, Song, Xiaoxia, Thomas, Gethin, Kenna, Tony, Leo, Paul, Brown, Matt (2017) Epigenetic and gene expression analysis of ankylosing spondylitis-associated loci implicate immune cells and the gut in the disease pathogenesis. Genes and Immunity, 18 (3), pp.135-143.

Lau, Max, Keith, Patricia, Costello, Mary-Ellen, Bradbury, Linda, Hollis, Kelly, Thomas, Ranjeny, Thomas, Gethin, Brown, Matt, Kenna, Tony (2017) Genetic association of ankylosing spondylitis with TBX21 influences T-bet and pro-inflammatory cytokine expression in humans and SKG mice as a model of spondyloarthritis. Annals of the Rheumatic Diseases, 76 (1), pp.261-269.

McInerney-Leo, Aideen, Wheeler, Lawrie, Marshall, Mhairi, Anderson, Lisa, Zankl, Andreas, Brown, Matt, Leo, Paul, Wicking, Carol, Duncan, Emma (2017) Homozygous variant in C21orf2 in a case of Jeune syndrome with severe thoracic involvement: Extending the phenotypic spectrum. American Journal of Medical Genetics, Part A, 173 (6), pp.1698-1704.

Wang, Xiaobing, Ellis, Jonathan, Pennisi, David, Song, Sharon, Batra, Jyotsna, Hollis, Kelly, Bradbury, Linda, Li, Zhixiu, Kenna, Tony, Brown, Matt (2017) Transcriptome Analysis of Ankylosing Spondylitis Patients Before and After TNF-α Inhibitor Therapy Reveals the Pathways Affected. Genes and Immunity, 18, pp.184-190.

Shi, Hongjun, Enriquez, Annabelle, Rapadas, Melissa, Martin, Ella, Wang, Roni, McInerney-Leo, Aideen, Leo, Paul, Brown, Matt, Duncan, Emma, other, and (2017) NAD deficiency, congenital malformations, and niacin supplementation. The New England Journal of Medicine, 377 (6), pp.544-552.

Ellinghaus, David, Jostins, Luke, Spain, Sarah, Cortes, Adrian, Bethune, Jorn, Brown, Matt, other, and (2016) Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. Nature Genetics, 48 (5), pp.510-518.

McInerney-Leo, Aideen, Harris, Jessica, Gattas, Michael, Peach, Elizabeth, Sinnott, Stephen, Dudding-Byth, Tracy, Rajagopalan, Sulekha, Barnett, Christopher, Wheeler, Lawrie, Anderson, Lisa, et al. (2016) Fryns syndrome associated with recessive mutations in PIGN in two separate families. Human Mutation, 37 (7), pp.695-702.

Robinson, Philip, Leo, Paul, Pointon, Jennifer, Harris, Jessica, Cremin, Katie, Bradbury, Linda, Stebbings, Simon, Harrison, Andrew, Duncan, Emma, Evans, David, et al. (2016) Exome-wide study of ankylosing spondylitis demonstrates additional shared genetic background with inflammatory bowel disease. npj Genomic Medicine, 1, pp.Article number: 16008 1-6.

McInerney-Leo, Aideen, Le Goff, Carine, Leo, Paul, Kenna, Tony, Keith, Patricia, Harris, Jessica, Steer, Ruth, Bole-Feysot, Christine, Nitschke, Patrick, Kielty, Cay, et al. (2016) Mutations in LTBP3 cause acromicric dysplasia and geleophysic dysplasia. Journal of Medical Genetics, 53 (7), pp.457-464.

Gregson, Celia, Wheeler, Lawrie, Hardcastle, Sarah, Appleton, Louise, Addison, Kathryn, Brugmans, Marieke, Clark, Graeme, Ward, Kate, Paggiosi, Margaret, Stone, Mike, et al. (2016) Mutations in known monogenic high bone mass loci only explain a small proportion of high bone mass cases. Journal of Bone and Mineral Research, 31 (3), pp.640-649.

Cortes, Adrian, Pulit, Sara, Leo, Paul, Pointon, Jennifer, Robinson, Philip, Weisman, Michael, Ward, Michael, Gensler, Lianne, Zhou, Xiaodong, Brown, Matthew, et al. (2015) Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1. Nature Communications, 6, pp.Article number: 7146 1-8.

Cortes, Adrian, Hadler, Johanna, Pointon, Jennifer, Robinson, Philip, Karaderi, Tugce, Leo, Paul, Cremin, Katie, Pryce, Karena, Harris, Jessica, Brown, Matthew, et al. (2013) Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci. Nature Genetics, 45 (7), pp.730-738.

Whyte, Jessica, Ellis, Jonathan, Brown, Matt, Kenna, Tony (2019) Best practices in DNA methylation: Lessons from inflammatory bowel disease, psoriasis and ankylosing spondylitis. Arthritis Research and Therapy, 21 (1), pp.Article number: 133 1-14.

Brown, Matt (2018) Solving the pathogenesis of ankylosing spondylitis. Clinical Immunology, 186, pp.46-50.

Hanson, Aimee, Brown, Matt (2017) Genetics and the causes of ankylosing spondylitis. Rheumatic Disease Clinics of North America, 43 (3), pp.401-414.

Brown, Matthew, Kenna, Tony, Wordsworth, Paul (B.P.) (2016) Genetics of ankylosing spondylitis - Insights into pathogenesis. Nature Reviews Rheumatology, 12 (2), pp.81-91.

Costello, Mary-Ellen, Robinson, Philip, Benham, Helen, Brown, Matthew (2015) The intestinal microbiome in human disease and how it relates to arthritis and spondyloarthritis. Best Practice and Research in Clinical Rheumatology, 29 (2), pp.202-212.