Functional Genomics Research

The Brown Lab Functional Genomics Group is made up of PhD students and postdoctoral researchers working under the supervision of Professor Matthew Brown and Dr Tony Kenna. The team utilises cell based, molecular biology, gene sequencing and animal modelling techniques to dig deep into the functional basis of genetic associations with complex immune-mediated diseases and cancers. The primary focus of the group lies in studying the immunological processes underlying the chronic spinal arthritis ankylosing spondylitis and fibrotic disease systemic sclerosis. A range of projects are underway to expand the current understanding of these debilitating conditions, with the goal of accelerating the development of targeted treatment for patients. The group has published widely in this space, and recent work can be found under the Publications tab.

Past and present projects in immune-mediated disease research can be found under the Projects tab.