Much of the work undertaken by academics and students in the Translational Research Group is entirely dependent on the generous contribution of biological samples from patients and healthy volunteers. In studying complex genetic diseases and cancers, samples from those primarily affected provide the best source of information as to the genetic and biological anomalies that may contribute to pathology. In the group, a range of clinical projects source primary human tissue for procedures such as DNA and RNA sequencing and genotyping, methylation profiling, cell culture, molecular biology assays and cell-based phenotyping. Current research projects undertaken by the lab can be viewed via the Projects tab.
The Ankylosing Spondylitis Clinic
The Ankylosing Spondylitis (AS) clinic at the Princess Alexandra Hospital was established in 2006. Professor Matthew Brown leads a team of clinicians, including two other consultant rheumatologists, registrars, physiotherapists, nurse practitioner and rheumatology nurse, to provide a multi-disciplinary approach to the management of people with AS – the first of its kind in Australia. The aim is to provide patients with education on the disease process, exercise and treatment options in a ‘one-stop shop’ model of care. The clinic also give patients the opportunity to participate in genetic research and clinical trials (if appropriate). If you are interested in attending the AS clinic or would like more information, please contact Linda Bradbury (nurse practitioner) on the AS clinic phone number +61 7 3443 7078.