2023
Menzel, Jan Philipp, Young, Reuben S.E., Benfield, Aurélie H., Scott, Julia S., Wongsomboon, Puttandon, Cudlman, Lukáš, Cvačka, Josef, Butler, Lisa M., Henriques, Sónia T., Poad, Berwyck L.J., & Blanksby, Stephen J. (2023) Ozone-enabled fatty acid discovery reveals unexpected diversity in the human lipidome. Nature Communications, 14, Article number: 3940. [https://eprints.qut.edu.au/244689/]
Wang, Conan K., Huang, Yen Hua, Shabbir, Fatima, Pham, Huong T., Lawrence, Nicole, Benfield, Aurélie H., van der Donk, Wilfred, Henriques, Sónia T., Turner, Mark S., & Craik, David J. (2023) The circular bacteriocin enterocin NKR-5-3B has an improved stability profile over nisin. Peptides, 167, Article number: 171049. [https://eprints.qut.edu.au/244687/]
Liu, Xiaorong, Henriques, Sónia T., Craik, David J., & Chan, Lai Yue (2023) Unlocking the Potential of the Antimicrobial Peptide Gomesin: From Discovery and Structure–Activity Relationships to Therapeutic Applications. International Journal of Molecular Sciences, 24(6), Article number: 5893. [https://eprints.qut.edu.au/244688/]
2022
Dias, Susana A., Pinto, Sandra N., Silva-Herdade, Ana S., Cheneval, Olivier, Craik, David J., Coutinho, Ana, Castanho, Miguel A.R.B., Henriques, Sónia T., & Veiga, Ana Salomé (2022) A designed cyclic analogue of gomesin has potent activity against Staphylococcus aureus biofilms. Journal of Antimicrobial Chemotherapy, 77(12), pp. 3256-3264. [https://eprints.qut.edu.au/237143/]
Edwards, Ingrid A., Henriques, Sónia T., Blaskovich, Mark A.T., Elliott, Alysha G., & Cooper, Matthew A. (2022) Investigations into the membrane activity of arenicin antimicrobial peptide AA139. Biochimica et Biophysica Acta – General Subjects, 1866(8), Article number: 130156. [https://eprints.qut.edu.au/234189/]
Amiss, Anna S., Henriques, Sónia Troeira, & Lawrence, Nicole (2022) Antimicrobial peptides provide wider coverage for targeting drug-resistant bacterial pathogens. Peptide Science, 114(2), Article number: e24246. [https://eprints.qut.edu.au/225978/]
Amiss, Anna S., von Pein, Jessica B., Webb, Jessica R., Condon, Nicholas D., Harvey, Peta J., Phan, Minh Duy, Schembri, Mark A., Currie, Bart J., Sweet, Matthew J., Craik, David J., Kapetanovic, Ronan, Henriques, Sónia Troeira, & Lawrence, Nicole (2022) Modified horseshoe crab peptides target and kill bacteria inside host cells. Cellular and Molecular Life Sciences, 79(1), Article number: 38. [https://eprints.qut.edu.au/234190/]
Nadal Bufi, Ferran, Chan, Lai Y., H. Mohammad, Hadi, Mason, Jody M., Salomón, Carlos, Lai, Andrew, Thompson, Rik, Craik, David J, Kaas, Quentin, & Troeira Henriques, Sonia (2022) Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation. Cellular and Molecular Life Sciences, 79(12), Article number: 606. [https://eprints.qut.edu.au/236338/]
2021
Philippe, Grégoire J.B., Craik, David J., & Henriques, Sónia T. (2021) Converting peptides into drugs targeting intracellular protein–protein interactions. Drug Discovery Today, 26(6), pp. 1521-1531 [https://eprints.qut.edu.au/208803/]
Nadal-Bufi, Ferran, Mason, Jody M., Chan, Lai Yue, Craik, David J., Kaas, Quentin, & Troeira Henriques, Sónia (2021) Designed β-Hairpins Inhibit LDH5 Oligomerization and Enzymatic Activity. Journal of Medicinal Chemistry, 64(7), pp. 3767-3779. [https://eprints.qut.edu.au/225979/]
Philippe, Grégoire J.B., Mittermeier, Anna, Lawrence, Nicole, Huang, Yen Hua, Condon, Nicholas D., Loewer, Alexander, Craik, David J., & Henriques, Sónia T. (2021) Angler Peptides: Macrocyclic Conjugates Inhibit p53:MDM2/X Interactions and Activate Apoptosis in Cancer Cells. ACS Chemical Biology, 16(2), pp. 414-428. [https://eprints.qut.edu.au/210157/]
Benfield, Aurélie H., Defaus, Sira, Lawrence, Nicole, Chaousis, Stephanie, Condon, Nicholas, Cheneval, Olivier, Huang, Yen Hua, Chan, Lai Yue, Andreu, David, Craik, David J., & Henriques, Sónia Troeira (2021) Cyclic gomesin, a stable redesigned spider peptide able to enter cancer cells. Biochimica et Biophysica Acta – Biomembranes, 1863(1), Article number: 183480. [https://eprints.qut.edu.au/208786/]
2020
Benfield, Aurelie & Troeira Henriques, Sonia (2020) Mode-of-Action of Antimicrobial Peptides: Membrane Disruption vs. Intracellular Mechanisms. Frontiers in Medical Technology, 2, Article number: 610997. [https://eprints.qut.edu.au/226706/]
Lawrence, Nicole, Philippe, Grégoire J.-B., Harvey, Peta J., Condon, Nicholas D., Benfield, Aurélie H., Cheneval, Olivier, Craik, David J., & Troeira Henriques, Sónia (2020) Cyclic peptide scaffold with ability to stabilize and deliver a helical cell-impermeable cargo across membranes of cultured cancer cells. RSC Chemical Biology, 1(5), pp. 405-420. [https://eprints.qut.edu.au/230300/]
Barth, Nicole D., Subiros-Funosas, Ramon, Mendive-Tapia, Lorena, Duffin, Rodger, Shields, Mario A., Cartwright, Jennifer A., Henriques, Sónia Troeira, Sot, Jesus, Goñi, Felix M., Lavilla, Rodolfo, Marwick, John A., Vermeren, Sonja, Rossi, Adriano G., Egeblad, Mikala, Dransfield, Ian, & Vendrell, Marc (2020) A fluorogenic cyclic peptide for imaging and quantification of drug-induced apoptosis. Nature Communications, 11(1), Article number: 4027. [https://eprints.qut.edu.au/204138/]
Nadal‐Bufí, Ferran & Henriques, Sónia Troeira (2020) How to overcome endosomal entrapment of cell‐penetrating peptides to release the therapeutic potential of peptides? Peptide Science, 112(6), Article number: e24168. [https://eprints.qut.edu.au/204189/]
Amiss, Anna S., Webb, Jessica R., Mayo, Mark, Currie, Bart J., Craik, David J., Henriques, Sónia Troeira, & Lawrence, Nicole (2020) Safer in Vitro Drug Screening Models for Melioidosis Therapy Development. American Journal of Tropical Medicine and Hygiene, 103(5), pp. 1846-1851. [https://eprints.qut.edu.au/208771/]
Peacock, Hayden, Henriques, Sónia Troeira, Benfield, Aurélie H, Elliott, Alysha G, Luo, Jinghui, Luccarelli, James, Nagano, Masanobu, Craik, David J, & Hamilton, Andrew D (2020) Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: Synthesis, conformational analysis and activity. ChemMedChem, 15(20), pp. 1932-1939. [https://eprints.qut.edu.au/204323/]
Skalska, Julia, Andrade, Vitor M., Cena, Gabrielle L., Harvey, Peta J., Gaspar, Diana, Mello, Érica O., Henriques, Sónia T., Valle, Javier, Gomes, Valdirene M., Conceição, Katia, Castanho, Miguel A. R. B., & Andreu, David (2020) Synthesis, structure, and activity of the antifungal plant defensin PvD1. Journal of Medicinal Chemistry, 63(17), 9391–9402. [https://eprints.qut.edu.au/204442/]
Du, Qingdan, Chan, Lai Y., Gilding, Edward K., Henriques, Sónia Troeira, Condon, Nicholas D., Ravipati, Anjaneya S., Kaas, Quentin, Huang, Yen Hua, & Craik, David J. (2020) Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus. The Journal of Biological Chemistry, 295(32), pp. 10911-10925. [https://eprints.qut.edu.au/204349/]
Sorolla, Anabel, Wang, Edina, Golden, Emily, Duffy, Ciara, Troeira Henriques, Sonia, Redfern, Andrew, & Blancafort, Pilar (2020) Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics. Oncogene, 39(6), pp. 1167-1184. [https://eprints.qut.edu.au/134022/]
2019
Vernen, Felicitas, Craik, David, Lawrence, Nicole, & Troeira Henriques, Sonia (2019) Cyclic Analogues of Horseshoe Crab Peptide Tachyplesin i with Anticancer and Cell Penetrating Properties. ACS Chemical Biology, 14(12), pp. 2895-2908. [https://eprints.qut.edu.au/197162/]
Sang, Jianrong, Kulkarni, Ketav, Watson, Gabrielle, Ma, Xiuquan, Craik, David, Troeira Henriques, Sonia, Poth, Aaron, Benfield, Aurelie, & Wilce, Jacqueline (2019) Evaluation of cyclic peptide inhibitors of the Grb7 breast cancer target: Small change in cargo results in large change in cellular activity. Molecules, 24(20), Article number: 37391-19. [https://eprints.qut.edu.au/134023/]
Philippe, Gregoire, Gaspar, Diana, Sheng, Caibin, Huang, Yen-Hua, Benfield, Aurelie, Condon, Nicholas, Weidmann, Joachim, Lawrence, Nicole, Loewer, Alexander, Castanho, Miguel, Craik, David, & Troeira Henriques, Sonia (2019) Cell membrane composition drives selectivity and toxicity of designed cyclic helix-loop-helix peptides with cell penetrating and tumor suppressor properties. ACS Chemical Biology, 14(9), pp. 2071-2087. [https://eprints.qut.edu.au/132056/]
Oshiro, Karen, Candido, Elizabete, Chan, Angeline Lai, Torres, Marcelo, Monges, Bruna, Rodrigues, Silvia, Porto, William, Ribeiro, Suzana, Troeira Henriques, Sonia, Lu, Timothy, Fuente-Nunez, Cesar, Craik, David, Franco, Octavio, & Cardoso, Marlon (2019) Computer-aided design of mastoparan-like peptides enables the generation of nontoxic variants with extended antibacterial properties. Journal of Medicinal Chemistry, 62(17), pp. 8140-8151. [https://eprints.qut.edu.au/132214/]
Vernen, Felicitas, Harvey, Peta, Dias, Susana, Veiga, Ana, Huang, Yen-Hua, Craik, David, Lawrence, Nicole, & Troeira Henriques, Sonia (2019) Characterization of tachyplesin peptides and their cyclized analogues to improve antimicrobial and anticancer properties. International Journal of Molecular Sciences, 20(17), Article number: 41841-25. [https://eprints.qut.edu.au/132327/]
Lawrence, Nicole, Wu, Bin, Ligutti, Joseph, Cheneval, Olivier, Agwa, Akello, Benfield, Aureilie, Biswas, Kaustav, Craik, David, Miranda, Les, Troeira Henriques, Sonia, & Schroeder, Christina (2019) Peptide-membrane interactions affect the inhibitory potency and selectivity of spider toxins ProTx-II and GpTx-1. ACS Chemical Biology, 14(1), pp. 118-130. [https://eprints.qut.edu.au/124529/]
Troeira Henriques, Sonia, Peacock, Hayden, Benfield, Aurelie, Wang, Conan, & Craik, David (2019) Is the Mirror Image a True Reflection? Intrinsic Membrane Chirality Modulates Peptide Binding. Journal of the American Chemical Society, 141(51), pp. 20460-20469. [https://eprints.qut.edu.au/197167/]
2018
Lawrence, Nicole, Dennis, Adelaide, Lehane, Adele, Ehmann, Anna, Harvey, Peta, Benfield, Aureilie, Cheneval, Olivier, Troeira Henriques, Sonia, Craik, David, & McMorran, Brendan (2018) Defense peptides engineered from human platelet factor 4 kill plasmodium by selective membrane disruption. Cell Chemical Biology, 25(9), pp. 1140-1150. [https://eprints.qut.edu.au/124528/]
Agwa, Akello, Peigneur, Steve, Chow, Chun Yuen, Lawrence, Nicole, Craik, David, Tytgat, Jan, King, Glenn, Troeira Henriques, Sonia, & Schroeder, Christina (2018) Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes. Journal of Biological Chemistry, 293(23), pp. 9041-9052. [https://eprints.qut.edu.au/124527/]
Perez Peinado, Clara, Dias, Susana, Domingues, Marco, Benfield, Aureilie, Freire, Joao, Radis-Baptista, Gandhi, Gaspar, Diana, Castanho, Miguel, Craik, David, Troeira Henriques, Sonia, Veiga, Ana, & Andreu, David (2018) Mechanisms of bacterial membrane permeabilization by crotalicidin (Ctn) and its fragment Ctn(15-34), antimicrobial peptides from rattlesnake venom. Journal of Biological Chemistry, 293(5), pp. 1536-1549. [https://eprints.qut.edu.au/124531/]
Madio, Bruno, Peigneur, Steve, Chin, Yanni, Hamilton, Brett, Troeira Henriques, Sonia, Smith, Jennifer, Cristofori-Armstrong, Ben, Dekan, Zoltan, Boughton, Berin, Alewood, Paul, Tytgat, Jan, King, Glenn, & Undheim, Eivind (2018) PHAB toxins: a unique family of predatory sea anemone toxins evolving via intra-gene concerted evolution defines a new peptide fold. Cellular and Molecular Life Sciences, 75(24), pp. 4511-4524. [https://eprints.qut.edu.au/124530/]
Velkov, Tony, Gallardo-Godoy, Alejandra, Swarbrick, James, Blaskovich, Mark, Elliott, Alysha, Han, Meiling, Thompson, Philip, Roberts, Kade, Huang, Johnny, Becker, Bernd, Troeira Henriques, Sonia, & other, and (2018) Structure, function, and biosynthetic origin of octapeptin antibiotics active against extensively drug-resistant gram-negative bacteria. Cell Chemical Biology, 25(4), pp. 380-391. [https://eprints.qut.edu.au/124532/]