Associate Professor Tim Dargaville

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Associated Investigator, QUT

PhD (University of Queensland)

Research theme: Health Research discipline: Chemistry Research program:Tissue Repair & Regeneration COVID-19 update: we are currently putting together a leading opinion article or immediate release addressing reuse of facial respirators with key recommendations. 29/3/202 Website: https://research.qut.edu.au/pnb/ Research area The inspiration behind A/Prof Dargaville's research is the development of new polymers and fabricated devices to help solve a number of important biomedical challenges. He has published 81 papers including 4 book chapters and made important contributions to the field of materials science and polymer chemistry. His areas of expertise include surface modification of polymers (PhD studies), effects of high energy radiation on polymers (post-doctoral position), synthesis of poly(2-oxazoline)s, biomaterials as implant devices, hydrogels for 3D cell culture and drug delivery devices (all part of current position at QUT). Skills include polymer synthesis (free radical and cationic mechanisms), polymer characterisation (a full suite of spectroscopic and analytical techniques), cell toxicity assays (e.g. to measure cytocompatibility of polymers with cells), and in vivo and ex vivo integration (using animal and ex vivo skin models to test biomaterial performance, integration and immune response). He is a consultant to hospitals, government laboratories and large/small companies in the areas of materials testing and new formulations.  Very recently he has contributed to an Australian Diabetics Research Foundation project aimed at delivering pancreatic islets to treat type I diabetes by developing a polymer scaffold capable of enhancing blood supply to the islets and improving their viability. Areas of expertise
  • Polymers
  • Biomaterials
  • Silicone polymers
  • Effects of radiation on materials including medical devices
Selected research projects
  • Poly(2-oxazoline)s as Biomaterials
  • Polymer scaffolds for tissue engineering of skin and percutaneous devices

Additional information

Title
Soft Materials Containing Hierarchy via 3d Sacrificial Micro-moulding
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
FT150100408
Start year
2016
Keywords
Title
Convergence of Biomaterials and Immunology - A Technology Platform for Delayed Burst Release of Vaccines
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
DP120104611
Start year
2012
Keywords
Vaccine Delivery; Delayed Burst Release; Electrospinning; Vaccine Implant; Immune Response
Title
Investigation of the Role of Transglutaminases in the Signalling of Insulin-like Growth Factor 1 and its Derivatives
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
LP110201004
Start year
2011
Keywords
Growth Factors; Cell Signalling; Wound Healing; Cancer
Title
Composite Biomaterials for Modulation of Dermal Fibroblast Function
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
DP0877988
Start year
2008
Keywords
Biomaterial; Hydrogel; Silicone; Fibroblast; Stratum Corneum