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PhD (Ecole Polytechnique Federale de Lausanne), MSc (Dipl. Phys. ETH) (Swiss Federal Institute of Technology (Zurich))
Dr Pascal Buenzli is a Senior Lecturer in Mathematical Biology at the School of Mathematical Sciences at QUT, and a former ARC DECRA Fellow 2013–2017. Academic experience
- 2020–: Senior Lecturer in Mathematical Biology, School of Mathematical Sciences, QUT
- 2017–2020: Lecturer in Mathematical Biology, School of Mathematical Sciences, QUT
- 2013–2017: ARC DECRA Fellow
- 2013–2017: Lecturer, School of Mathematical Sciences, Monash University
- 2009–2013: Research Assistant Professor, Engineering Computational Biology Group, The University of Western Australia
- 2007–2008: Postdoctoral Research Associate, Theoretical Physics, Universidad de Chile, Santiago, Chile
Education
- PhD in Theoretical Physics (with distinction), Swiss Federal Institute of Technology Lausanne (EPFL)
- MSc/Dipl. Phys. ETH, Swiss Federal Institute of Technology Zürich (ETHZ)
Additional information
Research Interests
- mathematical biology
- mechanobiology
- biological physics
- complex systems
- stochastic processes
- statistical mechanics and fluctuation-induced phenomena
Research Statement
My research is in mathematical modelling of biological tissue growth and remodelling. Such biological systems are subjected to mechanistic processes related to geometric constraints, mechanics, and mass balance that are well adapted to be captured by mathematical models. It is essential that we understand quantitatively the involvement of these mechanistic processes in observed experimental data to be able to interpret these data correctly. By factoring out these mechanistic processes, we gain access to less mechanistic, cell behavioural quantities that are highly relevant to biologists.
- Alias M, Buenzli P, (2017) Modeling the effect of curvature on the collective behavior of cells growing new tissue, Biophysical Journal p193-204
- Lerebours C, Buenzli P, Scheiner S, Pivonka P, (2016) A multiscale mechanobiological model of bone remodelling predicts site-specific bone loss in the femur during osteoporosis and mechanical disuse, Biomechanics and Modeling in Mechanobiology p43-67
- Buenzli P, (2016) Governing equations of tissue modelling and remodelling: A unified generalised description of surface and bulk balance, PLoS One p1-25
- Lerebours C, Buenzli P, (2016) Towards a cell-based mechanostat theory of bone: the need to account for osteocyte desensitisation and osteocyte replacement, Journal of Biomechanics p2600-2606
- Buenzli P, (2015) Osteocytes as a record of bone formation dynamics: A mathematical model of osteocyte generation in bone matrix, Journal of Theoretical Biology p418-427
- Buenzli P, Sims N, (2015) Quantifying the osteocyte network in the human skeleton, Bone p144-150
- Buenzli P, Pivonka P, Smith D, (2014) Bone refilling in cortical basic multicellular units: insights into tetracycline double labelling from a computational model, Biomechanics and Modeling in Mechanobiology p185-203
- Buenzli P, Pivonka P, Smith D, (2011) Spatio-temporal structure of cell distribution in cortical Bone Multicellular Units: A mathematical model, Bone p918-926
- Buenzli P, Martin P, (2008) Microscopic theory of the Casimir force at thermal equilibrium: Large-separation asymptotics, Physical Review E p1-15
- Buenzli P, Soto R, (2008) Violation of the action-reaction principle and self-forces induced by nonequilibrium fluctuations, Physical Review E p1-4