Find Laura Bray on
Evaluation of Fibroin based Scaffolds for Ocular Tissue Reco (Queensland University of Technology)
Dr Laura Bray is a Senior Lecturer and Deputy Director of the ARC Training Centre for Cell and Tissue Engineering Technologies. She graduated with first class honours in Biomedical Science followed by a PhD at QUT. At the end of 2012, Dr Bray was awarded the inaugural Prime Minister’s Queen Elizabeth II Diamond Jubilee Postdoctoral Award (awarded to only one woman in Australia), which she accepted and joined the group of Professor Carsten Werner at the Leibniz Institute for Polymer Research in Dresden, Germany. After 3 years working in Dresden, from 2013-2016, Dr Bray received a National Breast Cancer Foundation Postdoctoral Fellowship and a Cure Cancer Australia project grant and moved her research to the Institute of Health and Biomedical Innovation at the Queensland University of Technology in Australia in March 2016. Through the use of state of the art matrix engineering techniques, her work has led to a number of significant advances in knowledge in the area of 3D tissue engineering and culture techniques. Her work has helped to clarify the potential role of the matrix environment in 3D cell cultivation and has provided new insights into mimicking the natural tissue environment in vitro.
Website:
http://www.laurabrayresearch.org
Main areas of research:
– Development of 3D cancer models
– Role of angiogenesis in tumour development
– Cross-talk of cancer cells with their microenvironment
– Role of the surrounding microenvironment in cancer progression and metastasis
– Blood vessel formation and heterogeneity
Additional information
- Bray L, Binner M, Korner Y, von Bonin M, Bornhauser M, Werner C, (2017) A three-dimensional ex vivo tri-culture model mimics cell-cell interactions between acute myeloid leukemia and the vascular niche, Haematologica p1215-1226
- Binner M, Bray L, Friedrichs J, Freudenberg U, Tsurkan M, Werner C, (2017) Cell-instructive starPEG-heparin-collagen composite matrices, Acta Biomaterialia p70-80
- Bray L, Binner M, Freudenberg U, Werner C, (2017) Hydrogel-based in vitro models of tumor angiogenesis, Methods in Molecular Biology p39-63
- Taubenberger A, Bray L, Haller B, Shaposhnykov A, Binner M, Freudenberg U, Guck J, Werner C, (2016) 3D extracellular matrix interactions modulate tumour cell growth, invasion and angiogenesis in engineered tumour microenvironments, Acta Biomaterialia p73-85
- Dhawan A, von Bonin M, Bray L, Freudenberg U, Bejestani E, Werner C, Hofbauer L, Wobus M, Bornhauser M, (2016) Functional interference in the bone marrow microenvironment by disseminated breast cancer cells, Stem Cells p2224-2235
- Gillies P, Bray L, Richardson N, Chirila T, Harkin D, (2015) Isolation of microvascular endothelial cells from cadaveric corneal limbus, Experimental Eye Research p20-28
- Bray L, Binner M, Holzheu A, Friedrichs J, Freudenberg U, Hutmacher D, Werner C, (2015) Multi-parametric hydrogels support 3D in vitro bioengineered microenvironment models of tumour angiogenesis, Biomaterials p609-620
- Chwalek K, Bray L, Werner C, (2014) Tissue-engineered 3D tumor angiogenesis models: Potential technologies for anti-cancer drug discovery, Advanced Drug Delivery Reviews p30-39
- Bray L, George K, Hutmacher D, Chirila T, Harkin D, (2012) A dual-layer silk fibroin scaffold for reconstructing the human corneal limbus, Biomaterials p3529-3538
- Bray L, George K, Ainscough L, Hutmacher D, Chirila T, Harkin D, (2011) Human corneal epithelial equivalents constructed on Bombyx mori silk fibroin membranes, Biomaterials p5086-5091