Find Robyn Araujo on
Robyn Araujo's full profile, contact information and publications are available on:
PhD (Applied Mathematics) (Queensland University of Technology)
Dr Araujo's overarching career goal is to demonstrate the transformative power of mathematics in developing real insight and innovative solutions to fundamental problems in the Life Sciences. She has a special interest in cancer research, particularly cancer signal transduction and anti-cancer therapeutic strategies. Collectively, she has had over sixteen years of research experience within the field of theoretical biology, which has allowed her to develop both analytical and computational approaches to the elucidation of important problems in cell biology and medicine. Dr Araujo's recent mathematical work on cellular protein networks has changed our scientific understanding of the structure and function of cellular communication via molecular networks. Until recently, the sheer size and interconnectedness of these molecular networks has prevented us from being able to understand and predict likely network responses to pharmacological inhibition. This novel line of research is now pointing to the fundamental mathematical principles that govern how biological systems function at the molecular level, and is creating a new level of insight as to how new treatment strategies may be devised on an individualised/personalised basis.Projects (Chief investigator)
Additional information
- Araujo R, Liotta L, (2018) The topological requirements for robust perfect adaptation in networks of any size, Nature Communications, 9, pp. 1-12.
- Paris L, Magni R, Zaidi F, Araujo R, Saini N, Harpole M, Coronel J, Kirwan D, Steinberg H, Gilman R, Petricoin E, Nisini R, Luchini A, Liotta L, (2017) Urine lipoarabinomannan glycan in HIV-negative patients with pulmonary tuberculosis correlates with disease severity, Science Translational Medicine, 9 (420), pp. 1-11.
- Petricoin E, Espina V, Araujo R, Midura B, Yeung C, Wan X, Eichler G, Johann D, Qualman S, Tsokos M, Krishnan K, Helman L, Liotta L, (2007) Phosphoprotein pathway mapping: Akt/Mammalian target of rapamycin activation is negatively associated with childhood rhabdomyosarcoma survival, Cancer Research, 67 (7), pp. 3431-3440.
- Araujo R, Liotta L, Petricoin E, (2007) Proteins, drug targets and the mechanisms they control : the simple truth about complex networks, Nature Reviews Drug Discovery, 6 (11), pp. 871-880.
- Araujo R, McElwain S, (2006) A Mixture Theory for the Genesis of Residual Stresses in Growing Tissues II: Solutions to the Biphasic Equations for a Multicell Spheroid, SIAM Journal on Applied Mathematics, 66 (2), pp. 447-467.
- Liotta L, Araujo R, (2006) A control theoretic paradigm for cell signaling networks : a simple complexity for a sensitive robustness, Current Opinion in Chemical Biology, 10 (1), pp. 81-87.
- Araujo R, McElwain D, (2004) A History of the Study of Solid Tumour Growth: The Contribution of Mathematical Modelling, Bulletin of Mathematical Biology, 66, pp. 1039-1091.
- Araujo R, McElwain D, (2004) New Insights into Vascular Collapse and Growth Dynamics in Solid Tumors, Journal of Theoretical Biology, 228, pp. 335-346.