Liver Disease Theme

Liver disease is a huge and increasing burden on society; it can be due to a few different reasons including excessive alcohol consumption, viral infections, and non-alcoholic liver disease. Each of these causes may have a different molecular pathway of developing the disease pathology, but one common feature is there is an injury or insult to the liver. This injury then results in activation of the wound healing process; when this healing process goes awry, liver disease can develop, the first stage of which is liver fibrosis. Although our knowledge and understanding of the molecular pathways involved in liver fibrosis have increased over the past few years, the five projects that are part of the Liver Disease Theme aim to overcome the shortage of effective therapies still experienced.