2015 PhD, Queensland University of Technology 2003 Masters of Molecular Biology, University of Queensland 2001 Bachelor in Science, University of Queensland
2015 PhD, Queensland University of Technology
2003 Masters of Molecular Biology, University of Queensland
2001 Bachelor in Science, University of Queensland
Dr Rachel Okolicsanyi is an emerging early career researcher who recently completed her PhD in the Genomics Research Centre (2016) and was recently awarded a prestigious competitive national NHMRC-ARC Dementia Fellowship (2017-2022). Her PhD investigated the role of heparan sulfate proteoglycans (HSPGs) in neural lineage differentiation of adult human mesenchymal stem cells (hMSC). This work identified several HSPGs as potential new targets controlling neural fate specification to be applied to the development of improved models to examine and repair brain damage. Dr Okolicsanyi’s current work extends this research by comparing HSPG influence on fate determination in both hMSC and neural stem cell models to correlate any PG specific influences with dementia and plaque formation.
Dr Okolicsanyi has a Bachelor in Science (UQ) and a Masters of Molecular Biology (UQ). She worked in research for 6 years after graduating in 2003, initially in forensic and prenatal diagnostic research at AGRF in Brisbane. Following this she spent 2 years working at Newcastle University in the UK investigating associations between iron pathway gene polymorphisms and Acute Lymphoblastic Leukaemia. Returning from the UK, Dr Okolicsanyi undertook a research position at Griffith University researching the genetics of alcoholic brains.
- Okolicsanyi, Rachel, Griffiths, Lyn, Haupt, Larisa (2014) Mesenchymal stem cells, neural lineage potential, heparan sulfate proteoglycans and the matrix Developmental Biology, 388 (1), pp.1-10.
- Okolicsanyi, Rachel, Faure, Marion, Jacinto, Jose, Chacon Cortes, Diego Fernando, Chambers, Suzanne, Youl, Philippa, Haupt, Larisa, Griffiths, Lyn (2014) Association of the SNP rs2623047 in the HSPG modification enzyme SULF1 with an Australian Caucasian Breast Cancer Cohort Gene, 547 (1), pp.50-54.
- Okolicsanyi, Rachel, van Wijnen, Andre, Cool, Simon, Stein, Gary, Griffiths, Lyn, Haupt, Larisa (2014) Heparan sulfate proteoglycans and human breast cancer epithelial cell tumorigenicity Journal of Cellular Biochemistry, 115 (5), pp.967-976.
- Okolicsanyi, Rachel, Camilleri, Emily, Oikari, Lotta Emilia, Yu, Chieh, Cool, Simon, van Wijnen, Andre, Griffiths, Lyn, Haupt, Larisa (2015) Human mesenchymal stem cells retain multilineage differentiation capacity including neural marker expression after extended in vitro expansion PLoS One, 10 (9), pp.Article number: e0137255 1-29.
- Okolicsanyi, Rachel, Buffiere, Anne, Jacinto, Jose, Chacon Cortes, Diego Fernando, Chambers, Suzanne, Youl, Philippa, Haupt, Larisa, Griffiths, Lyn (2015) Association of heparan sulfate proteoglycans SDC1 and SDC4 polymorphisms with breast cancer in an Australian Caucasian population Tumor Biology, 36 (3), pp.1731-1738.
- Oikari, Lotta Emilia, Okolicsanyi, Rachel, Qin, Aro, Yu, Chieh, Griffiths, Lyn, Haupt, Larisa (2016) Cell surface heparan sulfate proteoglycans as novel markers of human neural stem cell fate determination Stem Cell Research, 16 (1), pp.92-104.
- Oikari, Lotta Emilia, Okolicsanyi, Rachel, Griffiths, Lyn, Haupt, Larisa (2016) Data defining markers of human neural stem cell lineage potential Data in Brief, 7, pp.206-215.
- Okolicsanyi, Rachel, Oikari, Lotta Emilia, Yu, Chieh, Griffiths, Lyn, Haupt, Larisa (2018) Heparan sulfate proteoglycans as drivers of neural progenitors derived from human mesenchymal stem cells Frontiers in Molecular Neuroscience, 11, pp.Article number: 134 1-16.