The Translational Neuro Therapeutics Program (TNTP) at the Translational Research Institute offers a comprehensive range of services tailored to industry needs, leveraging our expertise in Parkinson’s Disease (PD) and Amyotrophic Lateral Sclerosis (ALS). Our dedicated PC2-certified laboratory is fully equipped for advanced molecular biology applications, providing state-of-the-art infrastructure to support cutting-edge research.
We specialize in both in vivo and in vitro models for PD and ALS, enabling preclinical evaluation of therapeutic interventions. Our in-house animal models are meticulously designed and validated to replicate the pathophysiological and behavioral hallmarks of these neurodegenerative diseases. Similarly, our in vitro systems offer high-throughput platforms for mechanistic studies, drug screening, and biomarker discovery.
With our extensive experience in clinical trials and translational research, TNTP bridges the gap between basic science and clinical application. Whether you’re exploring novel therapeutic candidates, investigating disease mechanisms, or developing biomarkers, our team is committed to delivering high-quality, reliable data to support your objectives.
Preclinical Models
- Preclinical Models of Parkinson’s disease for drug and target validation
- Preclinical models of ALS for drug and target validation
- Gnotobiotic animal models to study the gut microbiome and gut-brain axi
In vitro models for CNS drug discovery
- Inflammasome activation assays
- In vitro models of neuroinflammation
- Primary neuron and microglia cultures
- In vitro models for neuroprotection in Parkinson’s and ALSs
TRI Core facilities
- TRI offers a wide range of Core Facilities to assist researchers from testing to analysis, and everything in between.
Consulting Services: Technical and Medical Writing
- Development of Clinical Strategy
- Protocol Development
- Preparation of Clinical Study Reports for FDA
- Development of Safety Update Reports for FDA, including Development Safety Update Reports (DSUR) and Periodic Safety Update Reports (PSUR)
- IND Assessment and Reviews
If you would like more information about any of these services, please don’t hesitate to reach out to us!