Chemotherapy Induced Peripheral Neuropathy Clinical Trial (CIPN)

A sequential multiple assignment randomised trial of nursing interventions to reduce pain associated with chemotherapy-induced peripheral neuropathy (CIPN study). 

Project dates:
Commenced: 2017
Completion: In progress

Peripheral neuropathy is a common side effect of chemotherapy.

Those who have peripheral neuropathy may experience weakness, numbness, tingling sensations and pain in their hands and feet.

The Chemotherapy Induced Peripheral Neuropathy (CIPN) clinical trial aims to find which self-managed treatments (heat or massage) reduce the symptoms of peripheral neuropathy.

Through this, researchers and participants will Test home-based, non-invasive methods for CIPN treatment – heat therapy (via a heat pad) and/or massage (via a massage ball) to:

• 1. Compare the effectiveness of the initial and adaptive interventions
• 2. Identify the best adaptive interventions embedded within the Sequential Multiple Assignment Randomized Trial (SMART) design
• 3. Evaluate the cost-effectiveness of each of the interventions
• 4. Blood samples for genomic analyses to evaluate differences in genotype distributions

QUT, in collaboration with our research partners and Queensland Health, is working hard to assist cancer patients to maintain a high-level quality of life after treatment.

The Chemotherapy Induced Peripheral Neuropathy (CIPN) clinical trial aims to improve the quality of life of those who are living with the pain and symptoms of peripheral neuropathy as a direct result of chemotherapy.

Please note: Recruitment for this trial has now closed.

This trial has been approved by the QUT Research Ethics Office. Our researchers follow the QUT Code of Conduct for Research.