Dr David Marshall

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Role in the centre

As a Research Infrastructure Specialist within the Central Analytical Research Facility (CARF), David is committed to developing cutting-edge mass spectrometry methods to support the research programs of QUT Centre Investigators and ECRs. Applying strategic and technical expertise in molecular mass spectrometry, David empowers HDR end-users through collaborative project development and tailored instrument training, ensuring the acquisition of high-quality data to strengthen research outputs. Evaluating user requirements and technological developments, David is also responsible for managing current instrumentation operations and contributing to future innovative advances in mass spectrometry at QUT. David has extensive experience in applying mass spectrometry to characterising soft matter materials, assaying catalyst performance, and elucidating unknown molecular structures.

Short biography

Dr David Marshall completed his PhD under the supervision of Dr Philip Barker and Prof. Stephen Blanksby at the University of Wollongong, studying the fate of radical-scavenging antioxidants in the preservation of painted steel rooftops. David joined QUT in 2014 as a Postdoctoral Fellow and played a key role in establishing the new Mass Spectrometry Development Laboratory within CARF. In partnership with local and international collaborators, David maintains a keen research interest in fundamental ion chemistry and spectroscopy to determine the structure, energetics, and reactivity of gaseous ions. Moreover, David is interested in applying these techniques to structure elucidation of synthetic and biological materials such as lipids, polymers, and molecular machinery. David has authored over 20 publications in high impact journals including Nature Chemistry, Angewandte Chemie, and Analytical Chemistry, which have collectively been cited over 300 times. David is an active member of the American Society for Mass Spectrometry, the Australia and New Zealand Society for Mass Spectrometry, and the Royal Australian Chemical Institute.

Selected publications

“Mapping enzyme activity on tissue by functional-mass spectrometry imaging” Hamilton B.R.; Marshall D.L.; Casewell N.R.; Harrison R.A.; Blanksby S.J.; Undheim E.A.B. Angew. Chem. Int. Ed. 2020, 59, 3855-3858.

“Introduction of a fixed-charge, photolabile derivative for enhanced structural elucidation of fatty acids” Narreddula V.R.; Boase N.R.; Ailuri R.; Marshall D.L.; Poad B.L.J.; Kelso M.J.; Trevitt A.J.; Mitchell T.W.; Blanksby S.J Anal. Chem. 2019, 91, 9901-9909.

“Polyselenoureas via multicomponent polymerizations using elemental selenium as monomer” Tuten B.T.; Bloesser F.R.; Marshall D.L.; Michalek L.; Schmitt C.W.; Blanksby S.J.; Barner-Kowollik C. ACS Macro Lett. 2018, 7, 898-903.

“Mass spectrometry-directed structure elucidation and total synthesis of ultra-long chain (O-acyl)-omega-hydroxy fatty acids” Hancock S.E.; Ailuri R.; Marshall D.L.; Brown, S.H.J.; Saville J.T.; Narreddula V.R.; Boase N.R.; Poad B.L.J.; Trevitt A.J.; Willcox M.D.P.; Kelso M.J.; Mitchell T.W.; Blanksby S.J. J. Lipid Res. 2018, 59, 1510-1518.

“Mass spectrometry imaging with isomeric resolution enabled by ozone-induced dissociation” Paine M.R.L.; Poad B.L.J.; Eijkel G.B.; Marshall D.L.; Blanksby S.J.; Heeren R.M.A.; Ellis S.R. Angew. Chem. Int. Ed. 2018, 57, 10530-10534.