Yi-Chin Toh

Associate Professor Yi-Chin Toh

Yi-Chin Toh is a Future Fellow and Associate Professor at the Queensland University of Technology. She obtained her B.Eng in Chemical Engineering and Ph.D in Bioengineering from the National University of Singapore in 2001 and 2008 respectively. She did her post-doctoral training at the Massachusetts Institute of Technology in 2008 under Professor Joel Voldman’s guidance. Before joining QUT, she was an Assistant Professor at the Department of Biomedical Engineering, National University of Singapore.

Yi-Chin leads the Micro Tissue Engineering Lab. Her major scientific contribution is in the advancement of microfluidic tissue models for applications in drug testing and experimental biology. To date, she has published over 40 papers in leading scientific journals such as Biomaterials and Lab on a Chip. Her current research interest is in engineering multi-scale tissue models to mimic complex biological interactions during human development and diseases, as well as translating them into scalable platforms for disease modeling and drug testing applications. Her lab is also working on integrating microfluidics and biofabrication technologies to realise a new generation of human-on-chips. Dr Toh is a recipient of the Australia Research Council Future Fellowship, National University of Singapore Research Scholarship, A*STAR Graduate Scholarship and A*STAR International Fellowship.

Contact

+61 7 3138 6170

yichin.toh@qut.edu.au

Selected publications

  1. Ong L, Ching T, Chong L, Arora S, Li H, Hashimoto M, DasGupta R, Yuen P, Toh Y, (2019) Self-aligning Tetris-Like (TILE) modular microfluidic platform for mimicking multi-organ interactions, Lab on a Chip, 19 (13), pp. 2178-2191.
  2. Sahni G, Chang S, Meng J, Tan J, Fatien J, Bonnard C, Utami K, Chan P, Tan T, Altunoglu U, Kayserili H, Pouladi M, Reversade B, Toh Y, (2021) A Micropatterned Human-Specific Neuroepithelial Tissue for Modeling Gene and Drug-Induced Neurodevelopmental Defects, Advanced Science, 8 (5).
  3. Ching T, Vasudevan J, Tan H, Lim C, Fernandez J, Toh Y, Hashimoto M, (2021) Highly-customizable 3D-printed peristaltic pump kit, HardwareX, 10.
  4. Ching T, Toh Y, Hashimoto M, Zhang Y, (2021) Bridging the academia-to-industry gap: organ-on-a-chip platforms for safety and toxicology assessment, Trends in Pharmacological Sciences, 42 (9), pp. 715-728.
  5. Ching T, Toh Y, Hashimoto M, (2020) Fabrication of Complex 3D Fluidic Networks via Modularized Stereolithography, Advanced Engineering Materials, 22 (3).
  6. Arora S, Lam A, Cheung C, Yim E, Toh Y, (2019) Determination of critical shear stress for maturation of human pluripotent stem cell-derived endothelial cells towards an arterial subtype, Biotechnology and Bioengineering, 116 (5), pp. 1164-1175.
  7. Ching T, Li Y, Karyappa R, Ohno A, Toh Y, Hashimoto M, (2019) Fabrication of integrated microfluidic devices by direct ink writing (DIW) 3D printing, Sensors and Actuators, B: Chemical, 297, pp. 1-9.
  8. Arora S, Lin S, Cheung C, Yim E, Toh Y, (2020) Topography elicits distinct phenotypes and functions in human primary and stem cell derived endothelial cells, Biomaterials, 234.
  9. Chong L, Li H, Wetzel I, Cho H, Toh Y, (2018) A liver-immune coculture array for predicting systemic drug-induced skin sensitization, Lab on a Chip, 18 (21), pp. 3239-3250.
  10. Ong L, Islam A, DasGupta R, Iyer N, Liang L, Toh Y, (2017) A 3D printed microfluidic perfusion device for multicellular spheroid cultures, Biofabrication, 9 (4), pp. 1-12.