
Project title
Membrane heparan sulfate proteoglycans in the breast cancer microenvironment
Supervisory Team
Principal Supervisor: Associate Professor Larisa Haupt
Associate Supervisors: Professor Lyn Griffiths, Dr Rachel Okolicsanyi
Project description
Son’s project has investigated the role of the cellular microenvironment in regulating human breast cancer (BC) models by examining members of the Heparan Sulfate Proteoglycan (HSPG) family of glycoproteins. Small interfering RNAs were used in vitro to inhibit HSPG gene expression and examine effects on target gene expression, cell proliferation and cell migration in BC cell lines. HSPGs can be considered as potential biomarkers for the early diagnosis and treatment of BC.
Short biography
Son is an MPhil student at QUT who completed BBiomedSci (Hons) at the University of the West of England, UK. He was awarded the Australian Government Research Training Program scholarship for the MPhil and became a member of the Genomic Research Centre in 2019.
Education
2018 Bachelor of Science (Honours) of Biomedical Science from the University of the West of England, United Kingdom
2016 Bachelor of Biotechnology from Vietnam National University, Vietnam