Associate Professor Daniel Wallace

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Chronic Disease Genomics Deputy Program Leader

PhD in Genetics (University of London)

Qualifications

  • PhD in Genetics - University College London (1999)
  • BSc (Hons) in Biochemistry - Sheffield University (1994)

Employment History

  • Research Officer / Senior Research Officer - QIMR Berghofer Medical Research Institute (2000-2016)
  • PhD Student - Royal Free Hospital School of Medicine, London (1996-1999)
  • Research Assistant - Royal Free Hospital School of Medicine, London (1994-1996)

Research Interests Dr Wallace’s main research interests lie in understanding the molecular bases underlying the control of iron homeostasis and iron associated disorders. He has published extensively in the fields of HFE and non-HFE haemochromatosis genetics, cell biology and the regulation of iron metabolism. His research over the past 20 years has been instrumental in defining the genetic causes of iron overload and the role of the liver and hepcidin in regulating body iron balance. He is also interested in how cancers exploit the iron regulatory machinery to increase iron availability for their growth and following from this the development of future therapeutics for cancer.

Additional information

Research Projects

Title
SARA: Delineating its Association with the Onset and Development of Liver Fibrosis
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1100088
Start year
2016
Keywords
Liver Injury; Signalling Pathways; Liver Fibrosis; Transforming Growth Factor Beta (TGF-beta); Animalmodel
Title
Delineating the Relationship between Iron and Peroxisomal Disorders: The Role of the Peroxisomal Enzyme GNPAT in Iron-Overload Disorders
Primary fund type
CAT 1 - Australian Competitive Grant
Project ID
1082224
Start year
2015
Keywords
Haemochromatosis; Iron Metabolism; Peroxisomal Disorders; Animal Model; Genetic Disorders