Short biography
Localised solid tumour cells metastases to secondary site via a series of phenotypic and gene expression changes known as epithelial-to-mesenchymal transition (EMT), resulting in a motile and invasive phenotype. Although “metastasis” and “EMT” are not commonly used to describe the dissemination of haematological malignancies, recent studies from our laboratory showed that high-risk t(4;14) multiple myeloma (MM) patients express an EMT-like gene signature, suggesting a role for EMT in MM. My PhD project will determine major regulatory events leading to EMT-like programme in the dissemination of MM and will identify ideal therapeutic targets to control the spread of MM in high-risk patients with aggressive disease.
Education
Bachelor of Science (Biomedicine), University of Adelaide
Bachelor of Health Sciences (Honours, First Class), University of Adelaide