A new technology that improves the biomanufacturing of biologics has been developed by Mr Zeyu Lu from the ARC Centre of Excellence in Synthetic Biology and CAB researcher Dr Bingyin Peng.
Temperature is a critical factor in the making of biologics, products derived from natural sources such as microorganisms and plants, including proteins and fine chemicals. LowTempGAL, outlined in a new paper, is a new system that helps to improve many aspects of the biomanufacturing process.
The LowTempGAL system uses temperature biosensors to regulate gene expression – the process by which a gene produces a product such as a protein.
‘It’s important to precisely control the expression of genes to optimise bioproduction and to interrogate fundamental questions about cellular metabolism’, says Dr Bingyin Peng.
To find out more, visit the ARC Centre of Excellence in Synthetic Biology website.