Development of an in vitro immunodiagnostic test for serum IgE specific to the major pollen allergen, Pas n 1, of the subtropical Bahia grass

Treatment of grass pollen allergy by immunotherapy reduces the risk of asthma but most reagents for diagnosis and treatment are based on cool climate grasses. We will develop a more specific diagnostic blood test for people with hay fever and allergic asthma triggered by subtropical Bahia grass pollen. This test based on the major allergen of Bahia grass pollen, Pas n 1, will help people who need improved accuracy of diagnosis and more effective treatment outcomes for hay fever and allergic asthma.


Funding / Grants

  • National Health and Medical Research Council (NHMRC) (2011 - 2014)

Chief Investigators

Team

Other Team Members

  • Professor John Upham, University of Queensland, Brisbane

Publications

  • Campbell, Bradley, Gilding, Edward, Timbrell, Victoria, Guru, Preethi, Loo, Dorothy, Zennaro, Danila, Mari, Adriano, Solley, Graham, Hill, Michelle, Godwin, Ian, et al. (2015) Total transcriptome, proteome, and allergome of Johnson grass pollen, which is important for allergic rhinitis in subtropical regions Journal of Allergy and Clinical Immunology, 135 (1), pp.133-142.